Grizzle grew up in Homewood and graduated from Homewood High School in 1993. She earned undergraduate degrees in math and English from Denison University in Granville, Ohio in 1997, a master's from UAB in 1999, and a doctorate on-line from Walden University in 2010. She did her student teaching in the Ensley area and joined Birmingham City Schools as a full-time teacher in 1999.
- "Grizzle advances to final four" (March 29, 2013) The Homewood Star
- Belanger, Evan (May 8, 2013) "Alison Grizzle of Birmingham City Schools named Alabama Teacher of the Year." The Birmingham News