Chamberlain graduated from Albert G. Parrish High School and attended Livingston University on a football and track scholarship. He left in 1968 to serve in the Marine Corps during the Vietnam War and afterwards completed a bachelor's degree in marketing at the University of Alabama in 1973. He went into marketing products for the shipbuilding, pulp and paper and power generation industries. He worked with prolific inventor Jack Gilbert and was inspired to successfully apply for two patents of his own.
- Chamberlain, Don N. (October 29, 1986) "Drain Valve" Patent No. 4,724,862 granted February 16, 1988
- Chamberlain, Donald N. (March 29, 1988) "Compressed Air Delivery System" Patent No. 4,830,056 granted May 16, 1989
- Diel, Stan (May 6, 2010) "Campaign 2010: 4 candidates hope to return U.S. House seat for Alabama District 7 to GOP." Birmingham News
- Don Chamberlain campaign website