November 22 in the history of the Birmingham District:
- 2010: Former amateur golfer and USGA executive Elbert Jemison died.
- 2008: UAB lost to Eastern Carolina 17-13 at Legion Field; Samford defeated Chattanooga 30-7.
- 2005: Chords of Relief was released.
- 2003: Auburn won the Iron Bowl 28-23 at home.
- 1997: Auburn won the Iron Bowl 18-17 at home.
- 1990: Homewood High School's marching band made their 4th appearance in the New York Macy's Thanksgiving Day Parade.
- 1982: Frank Stitt's Highlands Bar and Grill opened.
- 1977: The Birmingham Genealogical Society received tax-exempt status.
- 1970: Drummer Chris Fryar was born.
- 1964: Businessman Olin Barnes III was born.
- 1961: Shopkeeper Gus Jebeles died in Birmingham.
- 1948: Uncle Tom's Bar-B-Q opened on 6th Avenue South.
- 1948: Educational consultant Diane Rivers was born in Conway, Arkansas.
- 1922: 90 miners were killed in the 1922 Dolomite No. 3 Mine explosion.
- 1910: The 1910 Census Jubilee began.
- 1899: Writer Howell Vines was born.
- 1874: A tornado ripped through Montevallo, destroying half the city and killing 2 people.
- 1871: Coal miner and labor leader William Mailly was born in Pittsburgh, Pennsylvania.
- 1842: Attorney and manager of the Cotton and Produce Exchange John Phelan was born in Marion.