Lusco, the son of Sam and Josephine Lusco, served in the U. S. Air Force. He began his career as a worker for the L & N Railroad. He married Constance Mary DiGiorgio and, when he was laid off from the railroad, joined his father-in-law in the grocery business. He moved the store to its present location and was known for his generosity to neighborhood children and residents in need. He moved to Norwood after selling the store, and worked for a while at Peaches and Cream. They later moved to Pelham, where Lusco maintained a container garden.
Lusco died on Christmas Day, 2014, surrounded by family. He was survived by three children, five grandchildren, and two great-grandchildren. After a memorial service at Our Lady of the Valley Catholic Church, he was buried at Southern Heritage Cemetery in Pelham.