U.S. Highway 78

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U.S. Highway 78 (also known as U.S. Route 78) currently runs for 715 miles from I-240 in Memphis, Tennessee to US 17 in Charleston, South Carolina. Much of the route has been paralleled by the new Interstate 22 (Corridor X).

US 78 traverses the states of:

Notable cities along the route of the highway include:


  • "U.S. Route 78." Wikipedia, The Free Encyclopedia. 20 Nov 2006. [2].