Hughes grew up in Alabama and studied theater at UAB and appeared in several short films locally, including the features "V/H/S2" and "Pop Skull" written and directed by Adam Wingard. She has played the role of "Laura Panic" in several shorts.
Outside of acting, Hughes interned at Apple Computer and worked to produce podcasts and product videos. She appeared in walk-throughs for the iPod Shuffle 3G and Apple TV before moving to Google in a user experience design role. From there she took a job with Airbnb. In 2014 she launched an iOS app called "Romp" which functions as a diary of sexual experiences.
Hughes is also a musician, and has performed as a member of San Francisco's "The Tropics".