Nequette earned his bachelor of architecture at Auburn University and began working for Gresham Smith & Partners as a project architect. In 1996 he moved over to Garrison Barrett Group, where he met Jeff Dungan.
In 1999 Nequette and Dungan left to start up the firm of Dungan Nequette Architects, with a promised commission for Cahaba Valley Fire & Rescue. As the firm grew, Nequette also co-founded Tracery Interiors and Furnishing in 2003, The G Brand in 2009, and ActionSportsArt in 2010.
Nequette and Dungan split in 2015. Nequette moved his office, Nequette Architecture & Design to 2218 2nd Avenue North in downtown Birmingham. In 2016 he purchased the three-story W. S. Brown Mercantile Building, most recently occupied by Harold's Furniture and redeveloped it for retail and residential use, renaming it "The Thomas" in honor of his father. He added a penthouse set behind a terrace for new office space for the firm.
- Godwin, Brent (August 22, 2016) "Big plans in store for a Second Avenue North building." Birmingham Business Journal
- Godwin, Brent (November 8, 2017) "This exec is putting his fingerprints on downtown." Birmingham Business Journal
- Nequette Architecture & Design website