Bernstein grew up in Atlanta and studied jazz guitar at Monterey Peninsula College was a graduate of the Berklee School of Music in Boston, Massachusetts, where he performed in the school's Studio Band directed by Kevin Eubanks. He played with the Muscle Shoal Rhythm Section in the mid-1980s.
In 1985 he founded the Real Bottlenecking Company which manufactures replicas of old medicine bottles used by slide guitarists. That company operates as a division of his Planet Blue Productions which provides music services under contract. Bernstein's long-lived jingle for Southeastern Meats is well known in the area.
Bernstein was a long-time music instructor for the former UAB Special Studies department where he taught Music Songwriting, Beginning Harmonica and a variety of other community music classes and he participated in the "Blues in the Schools" program run by the Alabama School of Fine Arts and the Alabama Jazz Hall of Fame.
In November 2007 Bernstein was found shot in his Chevrolet Tracker outside of New Era Baptist Church on Cotton Avenue. He was survived by two daughters, Summer and Heather, and two granddaughters. He was interred at Elmwood Cemetery.
- Robinson, Carol (November 6, 2007) "Bernstein, longtime musician, fatally shot." Birmingham News.
- Scott "Blue" Bernstein profile at the Real Bottlenecking Company