Partridge earned his undergraduate degree at the University of Alabama and his medical degree at the UAB School of Medicine in 1973. He completed his residency in obstetrics and gynecology at UAB Hospital under a fellowship sponsored by the American Cancer Society. He joined the faculty in 1976 as an instructor and rose to director of the Division of Gynecologic Oncology in 1990 and was named to the Margaret Cameron Spain Chain in Obstetrics and Gynecology in 1999.
Partridge is currently the Evalina B. Spencer Chair of Oncology and assumed the role of acting director of the Comprehensive Cancer Center after the resignation of Peter Emanuel in July 2006 and assumed the full-time position in November 2007. He has led efforts to improve patient care in the Black Belt through the Alabama Black Belt Cancer Linkage Initiative and is a principal investigator for the Deep South Network for Cancer Control.
Partridge's involvement with the American Cancer Society included a role in establishing the Joe Lee Griffin Hope Lodge. He was elected President of the National Board of Directors for the ACS in 2010, and served a one-year term.
- "UAB Comprehensive Cancer Center director named president of American Cancer Society." (November 5, 2010) UAB Media Relations press release