- Pioneer John Jones departed from South Carolina.
- January 19: Mortimer Jordan, plantation owner
- December 5: Joshua Martin, Governor of Alabama
- Elisha Peck, Alabama Chief Justice
In 1799, Ranjit Singh the Great conquered Lahore and became ruler of the Punjab. Captain Pierre Bouchard discovered the Rosetta Stone. The HMS Lutine was sunk. The French Revolution ended with Napoleon Bonaparte's rise to power.
Notable births in 1799 included physician Karl Adolph von Basedow, cook Eliza Acton, paleontologist Mary Anning, author Alexander Pushkin, and inventor James Bowman Lindsay. Notable deaths included mathematician Maria Gaetana Agnesi, Qianlong Emperor of China, Indian ruler Tipu Sultan, American revolutionary politician Patrick Henry, Pope Pius VI, and first U.S. president George Washington.
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