Breeding earned his bachelor's degree in civil engineering at Vanderbilt University in Nashville, Tennessee. He worked with James Carr in the firm of Carr & Breeding until 1904, then partnered with David O. Whilldin in the firm of Breeding & Whilldin, with offices in the Watts Building, from 1904 to late 1906. The latter partnership's first and best-known commission was Birmingham High School, completed in 1906.
- Alston Building, Tuscaloosa, 1909
- Farley Building, 3rd Avenue and 20th Street North, 1909
- Ramsay-McCormack building, Avenue E and Ensley, Ensley, 1926
- Del-Mar Apartments
- 6th Avenue Presbyterian Church
- “Birmingham Architect Struck by Automobile Succumbs at Hospital,” (March 11, 1941) The Birmingham News
- Shelby, Thomas Mark (2006) "From Beaux-Arts to Modernism: The Alabama Architecture of D. O. Whilldin, 1881-1970" M.A. thesis, University of Alabama/UAB
- Shelby, Thomas Mark (April 2007) "D. O. Whilldin". Heritage Week 2007. Tuscaloosa County Preservation Society.