July 22 in the history of the Birmingham District:
- 2010: Bayou Deli opened on Birmingham Green.
- 2010: "Heads Up Alabama", an exhibit of twenty custom-painted oversize heads, went on display at the Birmingham Public Library.
- 2006: The Function in the Junction jazz festival was held in Erskine Hawkins Park in Ensley.
- 2005: Amani Raha hosted a private party before it opened to the public the following night.
- 1982: The 1982 Hewitt-Trussville High School building was officially dedicated.
- 1980: The Irondale Cafe reopened in a newly-rebuilt building.
- 1972: The Sloss Blast Furnace Site was added to the National Register of Historic Places.
- 1946: The Bromberg's building downtown held its grand opening.
- 1941: Joseph Raya was ordained a priest of the Melkite Catholic Church.
- 1922: Medal of Honor recipient Ross Gray enlisted in the Marine Corps Reserve in Birmingham.
- 1979: CD/DVD producer Bik Lonnie was born.
- 1957: Barber Tony Tarver was born.
- 1953: Jefferson County Manager Tony Petelos was born in Birmingham.
- 1934: Actress Louise Fletcher was born in Birmingham.
- 1930: Jazz musician and club owner Jerry Grundhoefer was born in St Paul, Minnesota.
- 1887: Businessman Beach Chenoweth was born in Jefferson County.
- 1840: Industrialist and founder of Bessemer Henry F. DeBardeleben was born in Montgomery County.
- 1835: Confederate officer and businessman Edmund Rucker was born in Tennessee.
- 2020: Basketball player Stanley Robinson died in Birmingham.
- 2017: Everett Holle, broadcaster
- 2013: Attorney Hugo Black, Jr died in Pinecrest, Florida.
- 1999: Commercial artist Dorothea Warren Fox died in New Fairfield, Connecticut.
- 1925: Drew Morris, son of William H. Morris, died.
- 1919: Edwin Taliaferro, attorney
- 2007: Andy Lally won the Porsche 250 at the Barber Motorsports Park.
- 2000: The Steeldogs lost 82-21 at Quad City Steamwheelers.