December 22 in the history of the Birmingham District:
- 2009: Circuit Court judge John Godbold died in Montgomery.
- 2007: Cincinnati defeated Southern Mississippi 31-21 in the second annual PapaJohns.com Bowl at Legion Field.
- 2001: Alabama Slammers lost 43-8 to the Jacksonville Dixie Blues
- 1992: Compass Bank acquired FWNB Bancshares of Carrollton, Texas.
- 1979: Western Lowland Gorilla Babec was born.
- 1969: The Homewood Board of Education was created, but did not yet assume authority.
- 1950: The last of Loveman's "Mr Bingle" shows with Benny Carle and Cliff Holman aired.
- 1929: A rare snowfall brought 5.5 inches to Birmingham.
- 1896: Bessie Parker, wife of A. H. Parker, died in childbirth.
- 1841: William Mudd married Florence Jane Earle.