April 27 in the history of the Birmingham District:
- 2011: The April 2011 tornado outbreak resulted in significant damage and fatalities throughout the Birmingham District.
- 2008: Kyle Busch won the Aaron's 499 at the Talladega Superspeedway.
- 2007: Magic City Art Connection at Linn Park.
- 2002: Birmingham Steeldogs 69 - Columbus Wardogs 29 at the BJCC Arena.
- 2001: Pop trio 3rd Faze signed a recording contract with GFI Productions, a subsidiary of HealthSouth.
- 1983: Evangelist Lee Roberson preached his final sermon at Highland Park Baptist Church in Chattanooga, Tennessee.
- 1980: Baseball player Mark Carter was born in Oneonta.
- 1941: Lee Roy Jordan was born in Monroe County.
- 1937: Art librarian Robert Kaufmann was born in Birmingham.
- 1927: Coretta Scott King was born in Perry County.
- 1927: Shot put champion Charlie Fonville was born in Birmingham
- 1925: Loew's Temple Theater opened.
- 1887: The City of Leeds was incorporated.
- 1865: Hundreds of Union prisoners, released from Cahawba prison during Wilson's Raid, died in the explosion of the riverboat Sultana near Memphis, Tennessee.
- 1860: Judge James Stiles was born in Oktibbeha County, Mississippi.