October 22 in the history of the Birmingham District:
- 2012: The historic covered Swann and Easley Bridges reopened to traffic after restoration.
- 2011: Broadcaster Ben McKinnon died.
- 2011: Actress Candace Bailey married Brian Corsetti.
- 2006: The Tragic City Rollers lost to the Atlanta Roller Girls 116 to 109.
- 2003: Tina Watson died while scuba diving in Australia with her husband Gabe.
- 1999: The Pelham Prowlers won 21-2 against the Tampa Bay Ice Pirates.
- 1995: Blind golfer and insurance executive Charley Boswell died.
- 1985: Boxer Deontay Wilder was born in Tuscaloosa.
- 1980: The Nabers, Morrow & Sinnige building was added to the National Register of Historic Places.
- 1955: Birmingham merchants sponsored a "Birmingham Days" concert at Municipal Auditorium.
- 1920: LSD advocate Timothy Leary was born.
- 1918: Baseball player and manager Harry "the Hat" Walker was born in Mississippi.
- 1915: 18 miners were killed in the 1916 Roden Mine explosion.
- 1912: Hugo Black retired from the Birmingham Police Court.
- 1886: The Birmingham Paint, Glass and Wall Paper Company was incorporated.
- 1867: Presbyterian pastor and insurance salesman Sterling Foster was born in Union Springs.
- 1855: Postmaster Maurice Throckmorton was born.