2023 is the 152nd year after the founding of the City of Birmingham.
- January 25: Chris Rock and Dave Chappelle co-headlined a comedy performance at Legacy Arena.
- January 28: 2023 Talladega County plane crash.
- February 26: The final print editions of The Birmingham News, The Huntsville Times and The Mobile Press-Register were distributed as Alabama Media Group shifted to all-digital delivery.
- May 4–6: The 2023 International Peace Conference was hosted in Birmingham.
- January: Maynard Cooper & Gale acquired Soltero Sapire Murrell of Austin, Texas.
- January: Birmingham Fastener & Supply acquired the Pacific Coast Bolt Corporation of Santa Fe Springs, California.
- April 1: Maynard Cooper & Gale merged with Nexsen Pruet of Columbia, South Carolina to form Maynard Nexsen.
- January 1: Alabama Power Company shut down its Gadsden Steam Plant.
- January: The Ensley Fairfield Mattress Co. closed.
- January: Norwood Clinic was acquired by Complete Health of Jacksonville, Florida.
- January 28: Interstellar Ginger Beer and Exploration Co. in Alabaster closed.
- March 1: St Vincent's Orthopedics was acquired by Hughston Clinic Orthopaedics of Phenix City.
- March 16 & 18: 2023 NCAA Men's Basketball Tournament first and second round.
- May 8–10: 2023 PGA WORKS Collegiate Championship at Shoal Creek Golf and Country Club and Bent Brook Golf Course
- July 8: The 2023 Move United Nationals were held in Birmingham and Hoover.
- 2023 Birmingham Barons (Minor League Baseball, Double-A South)
- 2023 Birmingham Legion FC (USL Championship)
- 2023 Birmingham Squadron (NBA G League)
- 2023 Birmingham Stallions (USFL)
- January 1: Ruth Bartow, widow of Gene Bartow
- January 7: James Roberson Sr, educator and auto dealer
- January 9: Ahmaad Galloway, educator and former running back
- January 11: Terry Oden, former Mayor of Mountain Brook
- January 13: Country Boy Eddie, musician and television host
- January 15: C. J. Harris, singer
- January 25: Ed Boutwell, founder of Boutwell Studios
- Buck Creek BnB in Helena
- The Cottages at Greystone
- Cullman Regional Medical Center 4-story tower
- Highlands College residence hall
- Magnolia City Place
- Northside Park
- Pepper Place Market market structure
- Powell Steam Plant
- The Star Uptown
- UAB Science & Engineering Complex
Notable people who died in 2023 include poet Charles Simic and musicians Jeff Beck, David Crosby, and Lisa Marie Presley.
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